Is Norephedrine, N-methyl- Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Norephedrine, N-methyl-? Is Norephedrine, N-methyl- safe for nursing mother and child? Does Norephedrine, N-methyl- extracts into breast milk? Does Norephedrine, N-methyl- has any long term or short term side effects on infants? Can Norephedrine, N-methyl- influence milk supply or can Norephedrine, N-methyl- decrease milk supply in lactating mothers?

An alkaloid derived from ephedra. It has sympathomimetic properties with direct and indirect effects on adrenergic receptors. Used parenterally to treat hypotension derived from spinal or epidural anesthesia due to its peripheral vasoconstrictor effects and improvement of heart tone. Used orally as a bronchodilator mixed in preparations for colds, bronchitis and asthma. Used illegaly as a psychostimulant and for weight loss, with serious health risks (van der Hoof 2002, Gruber 1998). See also information on Ephedra. Since the last update we have not found published data on its excretion in breast milk. Its large volume of distribution makes it unlikely it will pass into milk in significant amounts. After a cesarean section with epidural anesthesia and use of Norephedrine, N-methyl- there were no side effects in 100 newborns; the time of initial breastfeeding was not delayed with respect to newborns after cesareans under general anesthesia (Havas 2013). The use of Norephedrine, N-methyl- during delivery or cesarean section is not contraindicated with the early initiation of breastfeeding: as well as the unlikely excretion in breast milk there is a low amount of colostrum obtained by the newborn in the first hours of life. It may be desirable to minimize the continued use of oral preparations for colds/bronchitis which contain Norephedrine, N-methyl- since a case of crying, irritability and insomnia has been reported in a 3-month-old infant whose mother was taking a medication containing d-isoNorephedrine, N-methyl- and dexbrompheniramine (Mortimer 1977). Simple preparations (a single active ingredient per drug) are preferable and even more so during breastfeeding. Abusive use as a psychostimulant or antiobesity product entails serious risks to the health of the mother and the infant and should be avoided (van der Hoof 2002, Gruber 1998). Topical use of Norephedrine, N-methyl- (see information on topical Norephedrine, N-methyl-) as a complement to preparations for local anesthetic, dermatologicals, stomatologicals or ophthalmologicals is compatible with breastfeeding (WHO 2002). See below the information of these related products: