Question

I am a breastfeeding mother and i want to know if it is safe to use A 281? Is A 281 safe for nursing mother and child? Does A 281 extracts into breast milk? Does A 281 has any long term or short term side effects on infants? Can A 281 influence milk supply or can A 281 decrease milk supply in lactating mothers?

A 281 lactation summary

A 281 is unsafe in breastfeeding
  • DrLact safety Score for A 281 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of A 281 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that A 281 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using A 281 .
  • It is recommended to evaluate the advantage of not breastfeeding while using A 281 Vs not using A 281 And continue breastfeeding.
  • While using A 281 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About A 281 usage in lactation

In spite of the fact that it is highly attached to serum proteins should be avoid while nursing because it is a newly appeared medication, a long standing effect (10 – 15 days), possibility to alter the baby’s appetite, needs to be taken for a long time (months or years), poor effect on weight loosing. Hypo-caloric diet and exercise are advisable. Breastfeeding women recover their pre-pregnancy body weight sooner than bottle-feeding mothers.

Alternate Drugs for Antiobesity preparations. ATC A08

Orlistat(Low Risk)
Sibutramine(Unsafe)
Anfepramone(Dangerous)
Benfluorex-Hcl(Dangerous)
Ephedrine(Low Risk)
Fenfluramine(Unsafe)
Phentermine(Dangerous)
Rimonabant(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.