Is Acrivastine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Acrivastine? Is Acrivastine safe for nursing mother and child? Does Acrivastine extracts into breast milk? Does Acrivastine has any long term or short term side effects on infants? Can Acrivastine influence milk supply or can Acrivastine decrease milk supply in lactating mothers?
Acrivastine lactation summary
- DrLact safety Score for Acrivastine is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Acrivastine may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Acrivastine may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Acrivastine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Acrivastine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Acrivastine usage in lactation
First generation antihistaminic and alchylamine drug with a mild sedative effect.
Answer by DrLact: About Acrivastine usage in lactation
Small occasional doses of acrivastine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause drowsiness and other effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. The nonsedating antihistamines are preferred alternatives.
Acrivastine Side Effects in Breastfeeding
Relevant published information on acrivastine was not found as of the revision date. In one telephone follow-up study, mothers reported irritability and colicky symptoms 10% of infants exposed to various antihistamines and drowsiness was reported in 1.6% of infants. None of the reactions required medical attention.[1]
Acrivastine Possible Effects in Breastfeeding
Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[2][3] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[2] Whether lower oral doses of acrivastine have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs
Loratadine(Safe)
Acrivastine(Low Risk)
Hydroxyzine(Safe)
Doxylamine(Unsafe)
Fexofenadine(Safe)
Cyclizine(Low Risk)
Diphenhydramine(Low Risk)
Dimenhydrinate(Low Risk)
Levocetirizine(Low Risk)
Dexchlorpheniramine(Low Risk)
Ketotifen(Low Risk)
Desloratadine(Safe)
Clemastine(Low Risk)
Meclizine(Low Risk)
Chlorpheniramine(Low Risk)
Epinastine(Low Risk)
Cetirizine(Safe)
Triprolidine(Safe)
Carbinoxamine(Low Risk)
Brompheniramine(Low Risk)
Pyrilamine(Low Risk)
Azelastine(Low Risk)