Is Fisalamine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Fisalamine? Is Fisalamine safe for nursing mother and child? Does Fisalamine extracts into breast milk? Does Fisalamine has any long term or short term side effects on infants? Can Fisalamine influence milk supply or can Fisalamine decrease milk supply in lactating mothers?
Fisalamine lactation summary
- DrLact safety Score for Fisalamine is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Fisalamine is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Fisalamine does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Fisalamine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Fisalamine usage in lactation
Mesalazine is badly absorbed by the intestine, serum levels are low with scant excretion into breast milk. N-acetyl-5-ASA is an inactive metabolite which is excreted into breast milk but not higher than 10% of relative infant's dose. No harm effects among breastfed infants from treated mothers have been reported, except for rare cases of diarrhea reported in the 80's with the use of Mesalazine compounds different to Balsalazide. In a review of 121 cases and 121 controls, the authors failed to observe those findings. (Moretti, 1989). Expert consensus supports the compatibility of Mesalazine during breastfeeding.