Question

I am a breastfeeding mother and i want to know if it is safe to use 3,5,3-Tri-iodo-l-thyronine? Is 3,5,3-Tri-iodo-l-thyronine safe for nursing mother and child? Does 3,5,3-Tri-iodo-l-thyronine extracts into breast milk? Does 3,5,3-Tri-iodo-l-thyronine has any long term or short term side effects on infants? Can 3,5,3-Tri-iodo-l-thyronine influence milk supply or can 3,5,3-Tri-iodo-l-thyronine decrease milk supply in lactating mothers?

3,5,3-Tri-iodo-l-thyronine lactation summary

3,5,3-Tri-iodo-l-thyronine is safe in breastfeeding
  • DrLact safety Score for 3,5,3-Tri-iodo-l-thyronine is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 3,5,3-Tri-iodo-l-thyronine is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 3,5,3-Tri-iodo-l-thyronine does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 3,5,3-Tri-iodo-l-thyronine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 3,5,3-Tri-iodo-l-thyronine usage in lactation

Synthetic preparation of human thyroid hormone T3 used in the treatment of hypothyroidism. Since the last update, we have not found published data on its excretion in breast milk. T3 is a natural component of breast milk, found in small concentrations that may or may not depend on plasma levels (Zhang 2013, Oberkotter 1989, Jansson 1983, Mizuta 1983, Sato 1979). Its concentration in breast milk is much higher than that of levothyroxine (T4), which is usually undetectable (Jansson 1983, Sato 1979). Until there is more published data on this drug in relation to breastfeeding, safer known alternatives (levothyroxine) may be preferable, especially during the neonatal period and in case of prematurity. Associations which are experts in thyroid diseases recommend treatment with levothyroxine in breastfeeding mothers affected by hypothyroidism (Alexander 2017).
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