Is N1-p-Chlorophenyl-N5-isopropylbiguanide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N1-p-Chlorophenyl-N5-isopropylbiguanide? Is N1-p-Chlorophenyl-N5-isopropylbiguanide safe for nursing mother and child? Does N1-p-Chlorophenyl-N5-isopropylbiguanide extracts into breast milk? Does N1-p-Chlorophenyl-N5-isopropylbiguanide has any long term or short term side effects on infants? Can N1-p-Chlorophenyl-N5-isopropylbiguanide influence milk supply or can N1-p-Chlorophenyl-N5-isopropylbiguanide decrease milk supply in lactating mothers?
N1-p-Chlorophenyl-N5-isopropylbiguanide lactation summary
- DrLact safety Score for N1-p-Chlorophenyl-N5-isopropylbiguanide is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N1-p-Chlorophenyl-N5-isopropylbiguanide is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N1-p-Chlorophenyl-N5-isopropylbiguanide does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N1-p-Chlorophenyl-N5-isopropylbiguanide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N1-p-Chlorophenyl-N5-isopropylbiguanide usage in lactation
It is an anti-malaria compound that combines N1-p-Chlorophenyl-N5-isopropylbiguanide with Atovacuona. N1-p-Chlorophenyl-N5-isopropylbiguanide is considered to be an essential drug and compatible with BF by WHO.
Alternate Drugs for Antimalarials. ATC P01B
Chloroquine(Safe)
Hydroxychloroquine(Safe)
Mefloquine(Safe)
Pyrimethamine(Safe)
Quinine(Safe)
Atovaquone(Low Risk)
Primaquine(Low Risk)
Artemisinin(Safe)
Halofantrine-HCl(Unsafe)
Lumefantrine(Safe)
Primaquine Phosphate(Low Risk)
Proguanil(Safe)
Sulfadoxine(Low Risk)
Sulphormethoxine(Low Risk)
Quinine Sulfate(Safe)