Is UNII-88463U4SM5 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-88463U4SM5? Is UNII-88463U4SM5 safe for nursing mother and child? Does UNII-88463U4SM5 extracts into breast milk? Does UNII-88463U4SM5 has any long term or short term side effects on infants? Can UNII-88463U4SM5 influence milk supply or can UNII-88463U4SM5 decrease milk supply in lactating mothers?
UNII-88463U4SM5 lactation summary
- DrLact safety Score for UNII-88463U4SM5 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-88463U4SM5 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-88463U4SM5 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-88463U4SM5 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-88463U4SM5 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-88463U4SM5 usage in lactation
A low concentration is reached in breast milk. It is commercialized in several countries (not in Spain) together with Pyrimethamine (see the latter drug) as an anti-malarial drug: Fansidar: 20 parts of Sulphadoxine by 1 of Pyrimethamine. Manufacturers give a dosage for children weighing more than 5 kg.
Alternate Drugs for Antimalarials. ATC P01B
Chloroquine(Safe)
Hydroxychloroquine(Safe)
Mefloquine(Safe)
Pyrimethamine(Safe)
Quinine(Safe)
Atovaquone(Low Risk)
Primaquine(Low Risk)
Artemisinin(Safe)
Halofantrine-HCl(Unsafe)
Lumefantrine(Safe)
Primaquine Phosphate(Low Risk)
Proguanil(Safe)
Sulfadoxine(Low Risk)
Sulphormethoxine(Low Risk)
Quinine Sulfate(Safe)