Is NSC 1572 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC 1572? Is NSC 1572 safe for nursing mother and child? Does NSC 1572 extracts into breast milk? Does NSC 1572 has any long term or short term side effects on infants? Can NSC 1572 influence milk supply or can NSC 1572 decrease milk supply in lactating mothers?
NSC 1572 lactation summary
- DrLact safety Score for NSC 1572 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of NSC 1572 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that NSC 1572 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of NSC 1572 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using NSC 1572 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC 1572 usage in lactation
Intestinal, biliary and genitourinary antispasmodic with few bibliographical references. Since the last update, we have not found published data on its excretion in breast milk. According to the manufacturer, adverse reactions are very rare and mild (Atlantis 2003). Its use is authorized in small infants (Atlantis 2003). Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.
Alternate Drugs for Drugs for functional bowel disorders (Anticholinergics, Antispasmodics). ATC A03A-B,
Dicyclomine(Unsafe)
Atropine(Safe)
Glycopyrrolate(Unsafe)
Belladona(Unsafe)
Dicycloverine(Unsafe)
Phloroglucinol(Low Risk)
Otilonium Bromide(Safe)
Glycopyrronium Bromide(Unsafe)
Hyoscyamine(Low Risk)
Mebeverine Hydrochloride(Low Risk)
Pinaverium Bromide(Low Risk)
Prifinium Bromide(Low Risk)
Propantheline-Bromide(Low Risk)
Trimebutine maleate(Low Risk)
Piperidolate Hydrochloride(Low Risk)
Phloroglucin(Low Risk)
Daturine(Low Risk)