Is Bromure de pinaverium Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Bromure de pinaverium? Is Bromure de pinaverium safe for nursing mother and child? Does Bromure de pinaverium extracts into breast milk? Does Bromure de pinaverium has any long term or short term side effects on infants? Can Bromure de pinaverium influence milk supply or can Bromure de pinaverium decrease milk supply in lactating mothers?
Bromure de pinaverium lactation summary
- DrLact safety Score for Bromure de pinaverium is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Bromure de pinaverium may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Bromure de pinaverium may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Bromure de pinaverium low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Bromure de pinaverium We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Bromure de pinaverium usage in lactation
A Calcium channel blocker with spasmolytic activity on the intestine and antimuscarinic effects. At latest update no published data were found on excretion into breast milk.Pharmacokinetic data (moderately high molecular weight and high protein binding) make unlikely the passage into milk in significant amounts.Its low oral bioavailability hinders its passage into infant's plasma from ingested milk, except in preterm infants and immediate neonatal period, since they may exhibit an increased intestinal permeability. Anticholinergics may reduce milk production: take a minimum necessary dose and avoid prolonged treatment if decreased milk is observed.
Alternate Drugs for Drugs for functional bowel disorders (Anticholinergics, Antispasmodics). ATC A03A-B,
Dicyclomine(Unsafe)
Atropine(Safe)
Glycopyrrolate(Unsafe)
Belladona(Unsafe)
Dicycloverine(Unsafe)
Phloroglucinol(Low Risk)
Otilonium Bromide(Safe)
Glycopyrronium Bromide(Unsafe)
Hyoscyamine(Low Risk)
Mebeverine Hydrochloride(Low Risk)
Pinaverium Bromide(Low Risk)
Prifinium Bromide(Low Risk)
Propantheline-Bromide(Low Risk)
Trimebutine maleate(Low Risk)
Piperidolate Hydrochloride(Low Risk)
Phloroglucin(Low Risk)
Daturine(Low Risk)