Is UNII-7SCF54H12J Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-7SCF54H12J? Is UNII-7SCF54H12J safe for nursing mother and child? Does UNII-7SCF54H12J extracts into breast milk? Does UNII-7SCF54H12J has any long term or short term side effects on infants? Can UNII-7SCF54H12J influence milk supply or can UNII-7SCF54H12J decrease milk supply in lactating mothers?
UNII-7SCF54H12J lactation summary
- DrLact safety Score for UNII-7SCF54H12J is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-7SCF54H12J may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-7SCF54H12J may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-7SCF54H12J low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-7SCF54H12J We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-7SCF54H12J usage in lactation
A Calcium channel blocker with spasmolytic activity on the intestine and antimuscarinic effects. At latest update no published data were found on excretion into breast milk.Pharmacokinetic data (moderately high molecular weight and high protein binding) make unlikely the passage into milk in significant amounts.Its low oral bioavailability hinders its passage into infant's plasma from ingested milk, except in preterm infants and immediate neonatal period, since they may exhibit an increased intestinal permeability. Anticholinergics may reduce milk production: take a minimum necessary dose and avoid prolonged treatment if decreased milk is observed.
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