Is EINECS 251-845-9 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use EINECS 251-845-9? Is EINECS 251-845-9 safe for nursing mother and child? Does EINECS 251-845-9 extracts into breast milk? Does EINECS 251-845-9 has any long term or short term side effects on infants? Can EINECS 251-845-9 influence milk supply or can EINECS 251-845-9 decrease milk supply in lactating mothers?
EINECS 251-845-9 lactation summary
- DrLact safety Score for EINECS 251-845-9 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of EINECS 251-845-9 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that EINECS 251-845-9 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of EINECS 251-845-9 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using EINECS 251-845-9 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About EINECS 251-845-9 usage in lactation
Antispasmodic drug used for treatment of Irritable Colon Syndrome. At latest update, no relevant published data concerning excretion into breast milk were found. Pharmacokinetic data support the likelihood of significant excretion into breast milk, despite of the excretion in the milk of animals has shown to be poor (less than 0.1%). Side effects of Trimebutine are rare and generally mild. This medication is not authorized for children under 12 years old. However, it has been used in neonates and infants in some countries. Anticholinergic drugs may reduce milk production. Use the minimal necessary dose as possible and avoid long-term use whenever a decrease in milk production would appear. Do not use it soon after birth or in case of premature infant.
Alternate Drugs for Drugs for functional bowel disorders (Anticholinergics, Antispasmodics). ATC A03A-B,
Dicyclomine(Unsafe)
Atropine(Safe)
Glycopyrrolate(Unsafe)
Belladona(Unsafe)
Dicycloverine(Unsafe)
Phloroglucinol(Low Risk)
Otilonium Bromide(Safe)
Glycopyrronium Bromide(Unsafe)
Hyoscyamine(Low Risk)
Mebeverine Hydrochloride(Low Risk)
Pinaverium Bromide(Low Risk)
Prifinium Bromide(Low Risk)
Propantheline-Bromide(Low Risk)
Trimebutine maleate(Low Risk)
Piperidolate Hydrochloride(Low Risk)
Phloroglucin(Low Risk)
Daturine(Low Risk)