Is CCRIS 8511 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CCRIS 8511? Is CCRIS 8511 safe for nursing mother and child? Does CCRIS 8511 extracts into breast milk? Does CCRIS 8511 has any long term or short term side effects on infants? Can CCRIS 8511 influence milk supply or can CCRIS 8511 decrease milk supply in lactating mothers?
CCRIS 8511 lactation summary
- DrLact safety Score for CCRIS 8511 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of CCRIS 8511 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that CCRIS 8511 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of CCRIS 8511 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using CCRIS 8511 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CCRIS 8511 usage in lactation
A macrolide antibiotic that is approved for pediatric use. Frequently used in young infants At latest update no published data on excretion into breast milk were found. It has higher molecular weight and shorter half-life elimination span than other macrolide antibiotics like azithromycin and claritormycin that are excreted into breast milk in negligible amount.Until more published information about this drug regarding breastfeeding appears, it may be preferable a known and safer alternative, especially during the neonatal period and in cases of prematurity. Early exposure to macrolide antibiotics (especially erythromycin) has been linked to hypertrophic pyloric stenosis, even through breast milk, being it a reason to avoid them during the first month of breastfeeding. Take into account the possible negative results of bacterial cultures among febrile infants when their mothers are on antibiotics, as well as the possibility of gastroenteritis by altering the intestinal flora.
Alternate Drugs for Macrolide, Lincosamide and Streptogramin antibacterials. ATC J01F
Azithromycin(Safe)
Clarithromycin(Safe)
Clindamycin(Low Risk)
Telithromycin(Unsafe)
Roxithromycin(Safe)
Dalfopristin(Low Risk)
Dirithromycin(Low Risk)
Spiramycin(Safe)
Josamycin(Low Risk)
Lincomycin(Safe)
Midecamycin(Low Risk)
Quinupristin(Low Risk)
Lincomycin Hydrochloride(Safe)