Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 205-824-6? Is EINECS 205-824-6 safe for nursing mother and child? Does EINECS 205-824-6 extracts into breast milk? Does EINECS 205-824-6 has any long term or short term side effects on infants? Can EINECS 205-824-6 influence milk supply or can EINECS 205-824-6 decrease milk supply in lactating mothers?

EINECS 205-824-6 lactation summary

EINECS 205-824-6 is safe in breastfeeding
  • DrLact safety Score for EINECS 205-824-6 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of EINECS 205-824-6 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that EINECS 205-824-6 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of EINECS 205-824-6 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 205-824-6 usage in lactation

A Lincosamide type antibacterial drug which is structurally similar to clindamycin. As clindamycin, it is excreted in breast milk in clinically non-significant amount with no problems being reported in infants whose mothers were treated with it. Its low oral bioavailability that further decreases with simultaneous ingestion of food, hinders the drug passage to the infant plasma from ingested mother’s milk , except in preterm babies and immediate neonatal period, in which they may occur an increased intestinal permeability. Among infants whose mothers are treated with antibiotics, an alteration of the intestinal flora may appear. In case of infant's fever, the possibility of false negative results of bacterial cultures should be taken into account.

Alternate Drugs for Macrolide, Lincosamide and Streptogramin antibacterials. ATC J01F

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