Is NSC-2100 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC-2100? Is NSC-2100 safe for nursing mother and child? Does NSC-2100 extracts into breast milk? Does NSC-2100 has any long term or short term side effects on infants? Can NSC-2100 influence milk supply or can NSC-2100 decrease milk supply in lactating mothers?
NSC-2100 lactation summary
- DrLact safety Score for NSC-2100 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of NSC-2100 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that NSC-2100 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of NSC-2100 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC-2100 usage in lactation
Topically used as a 0.2% cream or ointment for the treatment of wounds, ulcers, skin infections and burns. At latest update relevant published data on its excretion into breast milk were not found. It is not absorbed in significant amounts into the systemic circulation, even when applied on burned surfaces (AEMPS 2007). The small dose used and low plasma uptake of most topical dermatological preparations make it unlikely that significant amounts would pass into breastmilk. Do not apply on the breast to prevent the infant from taking it; if necessary, do it after a feeding and clean it up thoroughly with water before the next one. It is toxic when taken by mouth, may cause contact dermatitis and hemolysis in cases of glucose-6-phosphate dehydrogenase deficiency (AEMPS 2007).
Alternate Drugs for Antibiotics and chemotherapeutics for dermatological, topical use. ATC D06
Erythromycin(Low Risk)
Mupirocin(Safe)
Fusidic Acid(Safe)
Bacitracin-Zinc(Safe)
Clindamycin Topical(Safe)
Gramicidin(Safe)
Nitrofural(Safe)
Silver Nitrate(Safe)
Sulfadiazine Silver(Low Risk)
Sulfanilamide(Safe)
Sulfathiazole(Low Risk)
Tyrothricin(Safe)
Fusafungine(Safe)
Sulfacetamide(Safe)
Chloramphenicol (topical use)(Low Risk)
Framycetin Sulfate(Safe)
Norsulfazole(Low Risk)
Silver Sulfadiazine(Low Risk)
Sulfacetamide Sodium(Safe)
Sulphanilamide(Safe)
Pseudomonic Acid(Safe)
Furacilin(Safe)
Furacilinum(Safe)
Nitrofurazone(Safe)