Is 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide? Is 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide safe for nursing mother and child? Does 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide extracts into breast milk? Does 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide has any long term or short term side effects on infants? Can 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide influence milk supply or can 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide decrease milk supply in lactating mothers?
6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide lactation summary
- DrLact safety Score for 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide usage in lactation
Because of a low absorption through skin significant excretion into breast milk is unlikely. Whenever a treatment for nipple eczema or dermatitis is required the lowest potency steroid compound should be used. It should be applied right after the feed to make sure it has disappeared before the next nursing occurs. Otherwise, wipe cream out with a clean gauze. Do not continuously use for longer than a week. Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple. Creams, gels or similar products that contain paraffin or mineral oil should not be used on the nipple to avoid absorption by the infant.
Alternate Drugs for Corticoid, dermatological, topical use. ATC D07A
Clobetasol(Safe)
Fluticasone, Topical(Safe)
Fluticasone, Inhaled(Safe)
Prednicarbate(Safe)
Beclomethasone Oral / Rectal(Low Risk)
Budesonide Oral(Safe)
Budesonide Rectal(Safe)
Clobetasol Propionate(Safe)
Fluticasone(Safe)
Fluocinolone Acetonide(Safe)
Mometasone Topical Use(Safe)
Fluocortolone(Safe)