Question

I am a breastfeeding mother and i want to know if it is safe to use NCI-C56564? Is NCI-C56564 safe for nursing mother and child? Does NCI-C56564 extracts into breast milk? Does NCI-C56564 has any long term or short term side effects on infants? Can NCI-C56564 influence milk supply or can NCI-C56564 decrease milk supply in lactating mothers?

NCI-C56564 lactation summary

NCI-C56564 usage has low risk in breastfeeding
  • DrLact safety Score for NCI-C56564 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of NCI-C56564 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that NCI-C56564 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of NCI-C56564 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using NCI-C56564 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NCI-C56564 usage in lactation

NCI-C56564 is an oleoresin contained in ripe and dry fruits of hot peppers. It is used for seasoning food and as medicine for topical analgesia in the form of creams, gels or patches. A low absorption into plasma (very low levels or undetectable in plasma) and rapid clearance make it highly unlikely the passage of significant amount toward breast milk. Do not apply on the chest or thoroughly clean it off before breastfeeding.

Alternate Drugs for Antiinflammatory preparations, non-steroids for topical use. ATC M02

Benzydamine Hydrochloride(Safe)
Capsaicin(Low Risk)
Carbenoxolone Sodium(Safe)
Dimethyl Sulfoxide(Low Risk)
Etofenamate(Low Risk)
Flufenamic Acid(Safe)
Triethanolamine Salicylate(Safe)
Trolamine Salicylate(Safe)

Synonyms of NCI-C56564

4-13-00-02588 (Beilstein Handbook Reference)
BRN 2816484
Capsaicine
Caswell No. 158
CCRIS 1588
EINECS 206-969-8
EPA Pesticide Chemical Code 070701
FEMA No. 3404
HSDB 954
N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide
(E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide
N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-
Isodecenoic acid vanillylamide
(E)-8-Methyl-N-vanillyl-6-nonenamide
trans-8-Methyl-N-vanillyl-6-nonenamide
8-Methyl-N-vanillyl-6-nonenamide, (E)-
6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-
6-Nonenamide, 8-methyl-N-vanillyl-, (E)-
NSC 56353
Styptysat
UNII-S07O44R1ZM
Qutenza
NGX-4010
NGX 4010
Zostrix
ALGRX 4975
Ausanil
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.