Is NSC 56353 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 56353? Is NSC 56353 safe for nursing mother and child? Does NSC 56353 extracts into breast milk? Does NSC 56353 has any long term or short term side effects on infants? Can NSC 56353 influence milk supply or can NSC 56353 decrease milk supply in lactating mothers?

NSC 56353 lactation summary

NSC 56353 usage has low risk in breastfeeding

DrLact safety Score for NSC 56353 is 3 out of 8 which is considered Low Risk as per our analyses.
A safety Score of 3 indicates that usage of NSC 56353 may cause some minor side effects in breastfed baby.
Our study of different scientific research indicates that NSC 56353 may cause moderate to no side effects in lactating mother.
Most of scientific studies and research papers declaring usage of NSC 56353 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
While using NSC 56353 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 56353 usage in lactation

NSC 56353 is an oleoresin contained in ripe and dry fruits of hot peppers. It is used for seasoning food and as medicine for topical analgesia in the form of creams, gels or patches. A low absorption into plasma (very low levels or undetectable in plasma) and rapid clearance make it highly unlikely the passage of significant amount toward breast milk. Do not apply on the chest or thoroughly clean it off before breastfeeding.