Is UNII-KZF0XM66JC Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-KZF0XM66JC? Is UNII-KZF0XM66JC safe for nursing mother and child? Does UNII-KZF0XM66JC extracts into breast milk? Does UNII-KZF0XM66JC has any long term or short term side effects on infants? Can UNII-KZF0XM66JC influence milk supply or can UNII-KZF0XM66JC decrease milk supply in lactating mothers?
UNII-KZF0XM66JC lactation summary
- DrLact safety Score for UNII-KZF0XM66JC is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-KZF0XM66JC may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-KZF0XM66JC may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-KZF0XM66JC low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-KZF0XM66JC We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-KZF0XM66JC usage in lactation
It is a non-steroidal anti-inflammatory which is derived from Flufenamic acid, topically used but it can also be orally or intravenously administered. At latest update relevant data related to breastfeeding were not found. However, we have information on its precursor the Flufenamic acid which is excreted into breast milk in non-significant amount and considered by the American Academy of Pediatrics as usual compatible with breastfeeding. Absorption from skin to the plasma has been reported. A high protein-binding capacity makes excretion into breast milk highly unlikely. However, it would be safer for both the mother and the infant the use of anti-inflammatory products with a proven safety while breastfeeding. Avoid the use on the nipple or on extensive skin areas or long-term treatments to prevent systemic absorption.
Alternate Drugs for Antiinflammatory preparations, non-steroids for topical use. ATC M02
Capsaicin(Low Risk)
Carbenoxolone Sodium(Safe)
Dimethyl Sulfoxide(Low Risk)
Etofenamate(Low Risk)
Flufenamic Acid(Safe)
Trolamine Salicylate(Safe)