Is Kabi-2165 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Kabi-2165? Is Kabi-2165 safe for nursing mother and child? Does Kabi-2165 extracts into breast milk? Does Kabi-2165 has any long term or short term side effects on infants? Can Kabi-2165 influence milk supply or can Kabi-2165 decrease milk supply in lactating mothers?
Kabi-2165 lactation summary
- DrLact safety Score for Kabi-2165 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Kabi-2165 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Kabi-2165 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Kabi-2165 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Kabi-2165 usage in lactation
This is a Heparin with low molecular weight There is scientific proof on the lack of excretion of Dalteparin into breast milk. The high molecular weight of the so-called Standard or non-fragmented Heparin and others called low weight Heparins makes that excretion into breast milk very unlikely. There is published evidence of a lack of anti-coagulant activity in the serum of breastfed infants whose mothers were treated with Enoxaparin. In addition, Heparin derived drugs are inactivated in the gut and they are not absorbed at all, hence, oral bioavailability is nil. The risk of Heparin-induced Thrombocytopenia and Osteoporosis is lower with low weight Heparin among treated adults.