Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 250-216-6? Is EINECS 250-216-6 safe for nursing mother and child? Does EINECS 250-216-6 extracts into breast milk? Does EINECS 250-216-6 has any long term or short term side effects on infants? Can EINECS 250-216-6 influence milk supply or can EINECS 250-216-6 decrease milk supply in lactating mothers?

EINECS 250-216-6 lactation summary

EINECS 250-216-6 is unsafe in breastfeeding
  • DrLact safety Score for EINECS 250-216-6 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of EINECS 250-216-6 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that EINECS 250-216-6 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using EINECS 250-216-6 .
  • It is recommended to evaluate the advantage of not breastfeeding while using EINECS 250-216-6 Vs not using EINECS 250-216-6 And continue breastfeeding.
  • While using EINECS 250-216-6 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 250-216-6 usage in lactation

Calcium-channel-blocking drug which is a piperazine derivative antihistamine with sedative effects.Used in prophylaxis of migraines and dizziness. At latest update no published data on excretion into breast milk were found.It may increase prolactin level (from Cortelli Formisano 1985 to 1991).Despite its high protein-binding capacity, because of a very long half-life span (18 days), there is a higher risk of excretion into breastmilk. A known and safer alternative should be preferred until more published data on this drug related to breastfeeding is available, - e.g. Propranolol, Metoprolol, Sertraline, Escitalopram, Amitrptilina or Valproate for Migraine prophylaxis (Pringsheim 2012, Davanzo 2014) and Nimodipine, Betahistine or Ginkgo biloba for vertigo prophylaxis, especially in the neonatal period and in case of prematurity.

Alternate Drugs for Anti-vertigo Drug

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