Question

I am a breastfeeding mother and i want to know if it is safe to use R-(-)-YM-12617? Is R-(-)-YM-12617 safe for nursing mother and child? Does R-(-)-YM-12617 extracts into breast milk? Does R-(-)-YM-12617 has any long term or short term side effects on infants? Can R-(-)-YM-12617 influence milk supply or can R-(-)-YM-12617 decrease milk supply in lactating mothers?

R-(-)-YM-12617 lactation summary

R-(-)-YM-12617 usage has low risk in breastfeeding
  • DrLact safety Score for R-(-)-YM-12617 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of R-(-)-YM-12617 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that R-(-)-YM-12617 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of R-(-)-YM-12617 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using R-(-)-YM-12617 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About R-(-)-YM-12617 usage in lactation

It is an alpha-1-adrenergic blocking agent that is used for treatment of benign prostate hypertrophy and troubles with urine voiding as obstruction or lithiasis. At latest update, relevant published data on excretion into breast milk were not found. Because of its pharmacokinetics (moderately high molecular weight and high protein-binding capacity) excretion into breast milk in significant amount is unlikely.
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