Is R-18134 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use R-18134? Is R-18134 safe for nursing mother and child? Does R-18134 extracts into breast milk? Does R-18134 has any long term or short term side effects on infants? Can R-18134 influence milk supply or can R-18134 decrease milk supply in lactating mothers?
R-18134 lactation summary
- DrLact safety Score for R-18134 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of R-18134 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that R-18134 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of R-18134 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About R-18134 usage in lactation
Excretion into breast milk is highly unlikely due to an almost nil systemic absorption through the skin, vaginal mucosa and even the intestine, with non-significant plasma levels (< 1 mcg/ mL) observed. In case of use on the nipple, let it be done after the feed and wipe it out any excess of cream before the next feed. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance. Miconazole has not been found to be more effective than pure lanolin for treatment of sore or cracked nipples. List of Essential Medicines by WHO 2002: compatible with breastfeeding.