Is Desmopressin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Desmopressin? Is Desmopressin safe for nursing mother and child? Does Desmopressin extracts into breast milk? Does Desmopressin has any long term or short term side effects on infants? Can Desmopressin influence milk supply or can Desmopressin decrease milk supply in lactating mothers?
Desmopressin lactation summary
- DrLact safety Score for Desmopressin is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Desmopressin is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Desmopressin does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Desmopressin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Desmopressin usage in lactation
It is structurally analogue to the naturally occurring anti-diuretic vasopressin hormone.
Answer by DrLact: About Desmopressin usage in lactation
Desmopressin from a nasal spray is excreted in negligible amounts into milk and is poorly absorbed orally by the infant, so it appears acceptable to use during breastfeeding. There is no published experience with sublingual desmopressin during breastfeeding. Until more data become available, sublingual desmopressin should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Desmopressin Possible Effects in Breastfeeding
Several cases have been reported of mothers with diabetes insipidus using desmopressin and breastfeeding their infants.[2][3][4] In one case, the mother discontinued nursing after 2 weeks because of a low milk supply, but this was not clearly drug related.[3] Lactation sometimes improves diabetes insipidus and reduces desmopressin requirements.[2][3]