Is Dichloralphenazone Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Dichloralphenazone? Is Dichloralphenazone safe for nursing mother and child? Does Dichloralphenazone extracts into breast milk? Does Dichloralphenazone has any long term or short term side effects on infants? Can Dichloralphenazone influence milk supply or can Dichloralphenazone decrease milk supply in lactating mothers?

Short-term or occasional use of dichloralphenazone during breastfeeding is unlikely to adversely affect the breastfed infant, especially if the infant is older than 2 months. Because the active metabolite, trichloroethanol, has a long half-life, long-term use of repeated doses during breastfeeding could result in infant sedation, especially while nursing a neonate or preterm infant. The low doses of dichloralphenazone found in combination migraine products (e.g., Midrin) are less likely to cause drowsiness in the infant unless doses are repeated several times daily. The antipyrine component of dichloralphenazone is considered unlikely to harm the infant.[1][2] Monitor the infant for excessive drowsiness during use.

Minimal morning sedation occurred in a 5-month-old breastfed infant whose mother was taking 1.3 grams of dichloralphenazone (equivalent to about 1 gram of chloral hydrate) every evening plus chlorpromazine 100 mg 3 times daily. The infant's overall development was said to be normal at 3 months of age.[3]