Question

I am a breastfeeding mother and i want to know if it is safe to use SKF 88373-Z? Is SKF 88373-Z safe for nursing mother and child? Does SKF 88373-Z extracts into breast milk? Does SKF 88373-Z has any long term or short term side effects on infants? Can SKF 88373-Z influence milk supply or can SKF 88373-Z decrease milk supply in lactating mothers?

SKF 88373-Z lactation summary

SKF 88373-Z is safe in breastfeeding
  • DrLact safety Score for SKF 88373-Z is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of SKF 88373-Z is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that SKF 88373-Z does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of SKF 88373-Z safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About SKF 88373-Z usage in lactation

Third-generation cephalosporin for injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Takase 1980, Motomura 1980, Gerding 1982, Matsuda 1984). Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.
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