Is Pefloxacine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pefloxacine? Is Pefloxacine safe for nursing mother and child? Does Pefloxacine extracts into breast milk? Does Pefloxacine has any long term or short term side effects on infants? Can Pefloxacine influence milk supply or can Pefloxacine decrease milk supply in lactating mothers?
Pefloxacine lactation summary
- DrLact safety Score for Pefloxacine is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Pefloxacine may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Pefloxacine may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Pefloxacine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Pefloxacine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Pefloxacine usage in lactation
Recently, quinolone-related medication has been used in neonates and infants without apparent side effects. It trespasses in tiny amounts into breast milk. Absorption through the child’s gut may be interfered by the calcium contained in the milk. Should it be necessary to prescribe it to a nursing mother, Norfloxacine, Ofloxacine and Ciprofloxacine have shown a lower level in the milk and thus must be the preferred drugs. Because a case of pseudomembranose colitis has been described possibly related to mother ingestion of Ciporfloxacine in a premature infant previously affected of NEC, a close follow-up for diarrhea is warranted. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics.
Alternate Drugs for Quinolone antibacterials. ATC J01M
Ciprofloxacin(Safe)
Enoxacin(Low Risk)
Gatifloxacin(Low Risk)
Levofloxacin(Low Risk)
Lomefloxacin(Low Risk)
Moxifloxacin(Low Risk)
Nalidixic Acid(Low Risk)
Norfloxacin(Safe)
Ofloxacin(Safe)
Trovafloxacin(Unsafe)
Garenoxacin(Low Risk)
Grepafloxacin(Unsafe)
Pefloxacin(Low Risk)
Pipemidic Acid(Unsafe)
Moxifloxacin Hydrochloride(Low Risk)