Question

I am a breastfeeding mother and i want to know if it is safe to use Tinidazole? Is Tinidazole safe for nursing mother and child? Does Tinidazole extracts into breast milk? Does Tinidazole has any long term or short term side effects on infants? Can Tinidazole influence milk supply or can Tinidazole decrease milk supply in lactating mothers?

Tinidazole lactation summary

Tinidazole is safe in breastfeeding
  • DrLact safety Score for Tinidazole is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Tinidazole is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Tinidazole does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Tinidazole safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Tinidazole usage in lactation

When administered orally or intravenously, it is excreted into breast milk in clinically non-significant amount which is very lower than that prescribed to infants. This medication is authorized for use in infants older than 1 month of age. Be aware of the possibility of false negative results of bacterial cultures done to infants when the mother is on antibiotics, together with a higher risk of diarrheal disease due to imbalance of intestinal flora. When topically used with creams and vaginal ovules, absorption into serum is scanty, hence, excretion into breast milk is believed lower than that attained by systemic administration.

Answer by DrLact: About Tinidazole usage in lactation

Amounts of tinidazole in milk are less than doses given to infants. Measurements of infant plasma levels during breastfeeding have not been reported. No studies have evaluated adverse effects of tinidazole on the infant during breastfeeding, but presumably they are similar to those of the closely related drug, metronidazole, such as increased risk of oral and rectal infections. As with metronidazole, concern has been raised about exposure of healthy infants to tinidazole via breastmilk,[1] because of possible mutagenicity and carcinogenicity. Opinions vary among experts on the advisability of using tinidazole during longer-term therapy while breastfeeding, but avoidance of breastfeeding for 3 days after a single dose should allow milk levels to drop to negligible values.[2] Other drugs are available for bacterial vaginosis, and can be given vaginally, which should result in lower amounts in breastmilk.

Alternate Drugs

Nelfinavir(Unsafe)
Cefepime(Safe)
Moxifloxacin(Low Risk)
Quinine(Safe)
Naftifine(Safe)
Capreomycin(Low Risk)
Aztreonam(Safe)
Cefprozil(Safe)
Ertapenem(Safe)
Malathion(Low Risk)
Zidovudine(Low Risk)
Cefdinir(Safe)
Indinavir(Unsafe)
Methicillin(Low Risk)
Tenofovir(Safe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Ofloxacin(Safe)
Primaquine(Low Risk)
Famciclovir(Low Risk)
Enoxacin(Low Risk)
Econazole(Safe)
Cefotetan(Safe)
Meropenem(Safe)
Saquinavir(Unsafe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Atovaquone(Low Risk)
Efavirenz(Unsafe)
Lindane(Unsafe)
Linezolid(Low Risk)
Didanosine(Unsafe)
Amikacin(Safe)
Neomycin(Safe)
Clindamycin(Low Risk)
Amantadine(Low Risk)
Lomefloxacin(Low Risk)
Rifaximin(Safe)
Ritonavir(Unsafe)
Valganciclovir(Low Risk)
Levofloxacin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Ganciclovir(Low Risk)
Nevirapine(Low Risk)
Nafcillin(Safe)
Acyclovir(Safe)
Dapsone(Low Risk)
Kanamycin(Safe)
Abacavir(Safe)
Moxifloxacin(Low Risk)
Capreomycin(Low Risk)
Aztreonam(Safe)
Cefprozil(Safe)
Mupirocin(Safe)
Ertapenem(Safe)
Cefdinir(Safe)
Iodine(Unsafe)
Methicillin(Low Risk)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Ofloxacin(Safe)
Methenamine(Unsafe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Neomycin(Safe)
Clindamycin(Low Risk)
Lomefloxacin(Low Risk)
Amikacin(Safe)
Nalidixic Acid(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Kanamycin(Safe)
Cefepime(Safe)
Quinine(Safe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.