Is L-Sulpiride Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use L-Sulpiride? Is L-Sulpiride safe for nursing mother and child? Does L-Sulpiride extracts into breast milk? Does L-Sulpiride has any long term or short term side effects on infants? Can L-Sulpiride influence milk supply or can L-Sulpiride decrease milk supply in lactating mothers?
L-Sulpiride lactation summary
- DrLact safety Score for L-Sulpiride is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of L-Sulpiride is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that L-Sulpiride does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of L-Sulpiride safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About L-Sulpiride usage in lactation
IL-enantiomer of Sulpiride. Both share similar characteristics and properties. More frequently used as anti-emetic and prokinetic than as anti-psychotic agent. Sulpiride is a Dopamine-selective antagonist that increases Prolactin serum levels which is used as anti-psychotic, anti-depressant, anti-emetic and prokinetic agent. Its property as galactogogue has been questioned because poor methodology used by published studies that intended to prove it. Doses at 50 mg twice-a-day after early post-partum for four weeks have been used to stimulate initiation of lactation without adverse effects in the mother. Excretion into breast milk is moderate, however, side-effects in breastfed infants from treated mothers were not observed. Best galactagogue effect is attained by promoting frequent breastfeeding on-demand along with the use of a proper lactation technique. Effective support to breastfeeding mothers, woman empowerment related to her ability to breastfeed and self-confidence are important factors to reinforce before start using galactagogue drugs.