Is Amphotericin B Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Amphotericin B? Is Amphotericin B safe for nursing mother and child? Does Amphotericin B extracts into breast milk? Does Amphotericin B has any long term or short term side effects on infants? Can Amphotericin B influence milk supply or can Amphotericin B decrease milk supply in lactating mothers?
Amphotericin B lactation summary
- DrLact safety Score for Amphotericin B is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Amphotericin B may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Amphotericin B may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Amphotericin B low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Amphotericin B We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Amphotericin B usage in lactation
On latest update relevant data on breastfeeding was not found. Poor or nil oral absorption and minimal secretion into breast milk are advanced. It has been used as a pediatric treatment even in newborns.
Answer by DrLact: About Amphotericin B usage in lactation
Although no information exists on the milk excretion of amphotericin B, it is highly protein bound, has a large molecular weight, is virtually unabsorbed orally and has been use directly in the mouths of infants;[1] therefore, most reviewers consider it acceptable to use in nursing mothers.[2][3]
Alternate Drugs
Tioconazole(Safe)
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Terbinafine(Safe)
Sulconazole(Safe)
Oxiconazole(Safe)
Naftifine(Safe)
Ciclopirox(Safe)
Butoconazole(Safe)
Amphotericin B(Low Risk)
Nystatin(Safe)
Salicylic Acid(Safe)
Miconazole(Safe)
Ketoconazole(Safe)
Itraconazole(Safe)
Fluconazole(Safe)
Clotrimazole(Safe)
Econazole(Safe)