Is AF-1161 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use AF-1161? Is AF-1161 safe for nursing mother and child? Does AF-1161 extracts into breast milk? Does AF-1161 has any long term or short term side effects on infants? Can AF-1161 influence milk supply or can AF-1161 decrease milk supply in lactating mothers?
AF-1161 lactation summary
- DrLact safety Score for AF-1161 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of AF-1161 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that AF-1161 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of AF-1161 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About AF-1161 usage in lactation
It is excreted into breast milk in clinically non-significant amount. Not effects on the infant's physical and psychomotor development at both short or long-term were found. Variable levels of Prolactin secretion (increment or lowering), which were non-significant, were found after the use of Trazodone. Because there is less experience published than with other drugs of the same pharmacological group, it should be preferred the use of an alternative drug that is known to be safer in the neonatal period or prematurity.