Question

I am a breastfeeding mother and i want to know if it is safe to use Flutamida [INN-Spanish]? Is Flutamida [INN-Spanish] safe for nursing mother and child? Does Flutamida [INN-Spanish] extracts into breast milk? Does Flutamida [INN-Spanish] has any long term or short term side effects on infants? Can Flutamida [INN-Spanish] influence milk supply or can Flutamida [INN-Spanish] decrease milk supply in lactating mothers?

Flutamida [INN-Spanish] lactation summary

Flutamida [INN-Spanish] usage has low risk in breastfeeding
  • DrLact safety Score for Flutamida [INN-Spanish] is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Flutamida [INN-Spanish] may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Flutamida [INN-Spanish] may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Flutamida [INN-Spanish] low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Flutamida [INN-Spanish] We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Flutamida [INN-Spanish] usage in lactation

Antiandrogenic drug that acts by blocking testosterone receptors which is used for treatment of prostate carcinoma.Not authorized for use in women although it is used for treatment of hirsutism with same or greater efficacy than Spironolactone (Erenus 1994 Cusan 1994, Moghetti 2000), androgenetic alopecia (Paradisi 2011). Also used for treatment of Polycystic Ovary Syndrome (Gambineri 2006). At latest update no published data on excretion into breast milk were found.Its high plasma protein-binding capacity makes it unlikely the excretion of significant amounts into breastmilk. Not alterations on prolactin level have been reported. Be aware that an aniline-containing metabolite would appear, which can lead under certain circumstances to develop Methemoglobinemia. A known and safer alternative should be preferred until more published data on this drug related to breastfeeding is available within the first 6 mo after birth, especially during the neonatal period and in case prematurity.Exposure through breastmilk may be minimized by waiting at least 6 hours before resuming breastfeed after the last dose of drug.

Alternate Drugs for Antineoplastic agents. Hormones & hormone antagonists. ATC L02

Flutamide(Low Risk)
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