Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-T58MSI464G? Is UNII-T58MSI464G safe for nursing mother and child? Does UNII-T58MSI464G extracts into breast milk? Does UNII-T58MSI464G has any long term or short term side effects on infants? Can UNII-T58MSI464G influence milk supply or can UNII-T58MSI464G decrease milk supply in lactating mothers?

UNII-T58MSI464G lactation summary

UNII-T58MSI464G is safe in breastfeeding
  • DrLact safety Score for UNII-T58MSI464G is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-T58MSI464G is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-T58MSI464G does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-T58MSI464G safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-T58MSI464G usage in lactation

Alpha-glucosidase inhibitor which acts within the gastrointestinal tract without being absorbed, reducing intestinal absorption of glucose. Very low risk of hypoglycemia in monotherapy. Since the last update we have not found any published data on its excretion in breast milk. Its pharmacokinetic data (moderately elevated molecular weight and very low intestinal absorption) make it unlikely that it would pass to breast milk in significant amounts (Serrano 2014, Everett 1997). Diet, exercise, and breastfeeding improve blood sugar levels.

Answer by DrLact: About UNII-T58MSI464G usage in lactation

Because less than 2% of a dose of UNII-T58MSI464G is absorbed from the mother's gastrointestinal tract, it is unlikely that any drug reaches the infant through breastmilk.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.