Question

I am a breastfeeding mother and i want to know if it is safe to use BRN 4338399? Is BRN 4338399 safe for nursing mother and child? Does BRN 4338399 extracts into breast milk? Does BRN 4338399 has any long term or short term side effects on infants? Can BRN 4338399 influence milk supply or can BRN 4338399 decrease milk supply in lactating mothers?

BRN 4338399 lactation summary

BRN 4338399 is unsafe in breastfeeding
  • DrLact safety Score for BRN 4338399 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of BRN 4338399 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that BRN 4338399 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using BRN 4338399 .
  • It is recommended to evaluate the advantage of not breastfeeding while using BRN 4338399 Vs not using BRN 4338399 And continue breastfeeding.
  • While using BRN 4338399 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About BRN 4338399 usage in lactation

It has been withdrawn from most countries because of severe liver toxic effects. Tiazolidindion drugs increase the response to insulin.Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus

Alternate Drugs for Oral blood glucose lowering drug (Anti-diabetic). Thiazolidinedione. ATC A10BG

Pioglitazone(Low Risk)
Rosiglitazone(Low Risk)
Troglitazone(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.