Is Calciben Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Calciben? Is Calciben safe for nursing mother and child? Does Calciben extracts into breast milk? Does Calciben has any long term or short term side effects on infants? Can Calciben influence milk supply or can Calciben decrease milk supply in lactating mothers?
Calciben lactation summary
- DrLact safety Score for Calciben is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Calciben is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Calciben does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Calciben safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Calciben usage in lactation
Hormone which is produced by the Thyroid gland as a polypeptide consisting of 32 amino acids that is used in the treatment of osteoporosis and other bone diseases and calcium metabolism.It is a natural component of breast milk as well as its predecessor, Procalcitonin, which is found in higher amount in milk than in plasma.Calcitonin levels increase during pregnancy and lactation.It has no effect on Prolactin and other Pituitary Hormones. Pharmacokinetic data (high molecular weight and rapid metabolism: Tmax and T1 / 2 short) makes it unlikely an excretion into breast milk in significant amounts. Because of a protein nature it is inactivated in the GI tract and hence not absorbed, so that their oral bioavailability is negligible, being unlikely any passage to the infant plasma, from ingested milk. An infant whose mother was treated with calcitonin every other day (plus azathioprine, warfarin, prednisone, acetaminophen, calcitriol, calcium and vitamins E and C) showed no problems after one year of lactation.