Is EINECS 241-145-1 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use EINECS 241-145-1? Is EINECS 241-145-1 safe for nursing mother and child? Does EINECS 241-145-1 extracts into breast milk? Does EINECS 241-145-1 has any long term or short term side effects on infants? Can EINECS 241-145-1 influence milk supply or can EINECS 241-145-1 decrease milk supply in lactating mothers?
EINECS 241-145-1 lactation summary
- DrLact safety Score for EINECS 241-145-1 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of EINECS 241-145-1 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that EINECS 241-145-1 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of EINECS 241-145-1 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About EINECS 241-145-1 usage in lactation
It is excreted into breastmilk in a clinically non-significant amount (Bader 1980, Brixen 1982, Pittard 1986, Breyer 1995, Yoshida 1999). Plasma levels in the infant have been found undetectable (Ericsson 1979, Bader 1980, Brixen 1982, Breyer 1995) or very low (Yoshida 1997) and no side effects being observed even at maternal doses as high as 150-175 mg / day (Brixen 1982 , Misri 1991, Yoshida 1999, Nulman 2002).However, one published case of sedation on a 15-day-old infant that occured within few days after taken just 10 mg daily of amitriptyline by her mother because of insomnia and anxiety (Oguz 2016). Levels were not measured in either milk or plasma of the infant and the mother. Amitriptyline may produce galactorrhoea by prolactin stimulation.