Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-741YH7379H? Is UNII-741YH7379H safe for nursing mother and child? Does UNII-741YH7379H extracts into breast milk? Does UNII-741YH7379H has any long term or short term side effects on infants? Can UNII-741YH7379H influence milk supply or can UNII-741YH7379H decrease milk supply in lactating mothers?

UNII-741YH7379H lactation summary

UNII-741YH7379H is safe in breastfeeding
  • DrLact safety Score for UNII-741YH7379H is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-741YH7379H is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-741YH7379H does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-741YH7379H safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-741YH7379H usage in lactation

At latest update no published data on excretion into breast milk were found. It has a negligible systemic absorption through skin or nails, which highly interfere with excretion into breast.It has been described sporadic neonatal use without observing side effects. Until more published information about this drug regarding breastfeeding appears, it may be preferable a known and safer alternative (topical Terbinafine, Floconazole), especially during the neonatal period and in cases of prematurity.
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