Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 253-538-5? Is EINECS 253-538-5 safe for nursing mother and child? Does EINECS 253-538-5 extracts into breast milk? Does EINECS 253-538-5 has any long term or short term side effects on infants? Can EINECS 253-538-5 influence milk supply or can EINECS 253-538-5 decrease milk supply in lactating mothers?

EINECS 253-538-5 lactation summary

EINECS 253-538-5 is safe in breastfeeding
  • DrLact safety Score for EINECS 253-538-5 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of EINECS 253-538-5 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that EINECS 253-538-5 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of EINECS 253-538-5 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 253-538-5 usage in lactation

Levels in the mother's milk are very low and in most instances undetectable. Like other aminoglycosides it is poorly absorbed in the intestine. Large doses may affect intestinal flora. Be aware of false negative bacterial cultures in the infant when the mother is on antibiotics. .

Answer by DrLact: About EINECS 253-538-5 usage in lactation

EINECS 253-538-5 is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of other aminoglycosides, but serum levels with typical three times daily dosages are far below those attained when treating newborn infections and systemic effects of EINECS 253-538-5 are unlikely. Older infants would be expected to absorb even less EINECS 253-538-5. Because there is little variability in the milk EINECS 253-538-5 levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.