Question

I am a breastfeeding mother and i want to know if it is safe to use Amperil? Is Amperil safe for nursing mother and child? Does Amperil extracts into breast milk? Does Amperil has any long term or short term side effects on infants? Can Amperil influence milk supply or can Amperil decrease milk supply in lactating mothers?

Amperil lactation summary

Amperil is safe in breastfeeding
  • DrLact safety Score for Amperil is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Amperil is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Amperil does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Amperil safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Amperil usage in lactation

Ampicillin is excreted in breast milk in clinically insignificant amounts (Rowe, 2013, Mylonas, 2011, Zhang, 1997, Fulton, 1992, Campbell 1991, Matsuda 1984), much lower than the dose used for newborns and infants ( Chin, 2000; Reali, 2005). No side effects have been observed in infants whose mothers were taking it except for some episodes of diarrhea or candidiasis due to altered intestinal flora (Chin, 2000). The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.