Is NCI-C56086 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NCI-C56086? Is NCI-C56086 safe for nursing mother and child? Does NCI-C56086 extracts into breast milk? Does NCI-C56086 has any long term or short term side effects on infants? Can NCI-C56086 influence milk supply or can NCI-C56086 decrease milk supply in lactating mothers?
NCI-C56086 lactation summary
- DrLact safety Score for NCI-C56086 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of NCI-C56086 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that NCI-C56086 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of NCI-C56086 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NCI-C56086 usage in lactation
Ampicillin is excreted in breast milk in clinically insignificant amounts (Rowe, 2013, Mylonas, 2011, Zhang, 1997, Fulton, 1992, Campbell 1991, Matsuda 1984), much lower than the dose used for newborns and infants ( Chin, 2000; Reali, 2005). No side effects have been observed in infants whose mothers were taking it except for some episodes of diarrhea or candidiasis due to altered intestinal flora (Chin, 2000). The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).