Is Cefuroxime 1-acetoxyethyl ester Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Cefuroxime 1-acetoxyethyl ester? Is Cefuroxime 1-acetoxyethyl ester safe for nursing mother and child? Does Cefuroxime 1-acetoxyethyl ester extracts into breast milk? Does Cefuroxime 1-acetoxyethyl ester has any long term or short term side effects on infants? Can Cefuroxime 1-acetoxyethyl ester influence milk supply or can Cefuroxime 1-acetoxyethyl ester decrease milk supply in lactating mothers?
Cefuroxime 1-acetoxyethyl ester lactation summary
- DrLact safety Score for Cefuroxime 1-acetoxyethyl ester is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Cefuroxime 1-acetoxyethyl ester is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Cefuroxime 1-acetoxyethyl ester does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Cefuroxime 1-acetoxyethyl ester safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Cefuroxime 1-acetoxyethyl ester usage in lactation
Second-generation cephalosporin for oral and injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Voropaeva 1982, Amiraslanova 1985, Nakamura 1987). No adverse effects reported in breasted infants (Benyamini 2005). Intravenously administered Cefuroxime salt is not orally absorbed. Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.