Is 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt? Is 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt safe for nursing mother and child? Does 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt extracts into breast milk? Does 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt has any long term or short term side effects on infants? Can 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt influence milk supply or can 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt decrease milk supply in lactating mothers?
7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt lactation summary
- DrLact safety Score for 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 7-(Thiophene-2-acetamido)cephalosporanic acid sodium salt usage in lactation
First-generation cephalosporin for injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Kafetzis 1981). Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.