Question

I am a breastfeeding mother and i want to know if it is safe to use Phyllocontin? Is Phyllocontin safe for nursing mother and child? Does Phyllocontin extracts into breast milk? Does Phyllocontin has any long term or short term side effects on infants? Can Phyllocontin influence milk supply or can Phyllocontin decrease milk supply in lactating mothers?

Phyllocontin lactation summary

Phyllocontin is safe in breastfeeding
  • DrLact safety Score for Phyllocontin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Phyllocontin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Phyllocontin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Phyllocontin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Phyllocontin usage in lactation

Its active metabolite is Theophylline (see it).

Answer by DrLact: About Phyllocontin usage in lactation

An expert panel considers use of Phyllocontin to be acceptable during breastfeeding.[1] Maternal Phyllocontin use may occasionally cause stimulation and irritability and fretful sleep in infants. Newborn and especially preterm infants are most likely to be affected because of their slow elimination and low serum protein binding of theophylline. There is no need to avoid Phyllocontin products; however, keep maternal serum theophylline concentrations in the lower part of the therapeutic range and monitor the infant for signs of theophylline side effects. Infant serum theophylline concentrations can help to determine if signs of agitation are due to theophylline. Avoiding breastfeeding for 2 hours after intravenous or 4 hours after an immediate-release oral Phyllocontin product can decrease the dose received by the breastfed infant.

Phyllocontin Side Effects in Breastfeeding

Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal Phyllocontin intake of 200 mg every six hours. These effects ceased with discontinuation and recurred on rechallenge over the next 9 months. These effects were probably caused by theophylline in breastmilk. Another five infants reported in this paper showed no adverse reactions after maternal theophylline ingestion.[3] Accumulation of theophylline in infant serum appears most likely in neonates and premature infants because they eliminate theophylline slowly.[2][5]

Synonyms of Phyllocontin

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.