Is UNII-27Y3KJK423 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use UNII-27Y3KJK423? Is UNII-27Y3KJK423 safe for nursing mother and child? Does UNII-27Y3KJK423 extracts into breast milk? Does UNII-27Y3KJK423 has any long term or short term side effects on infants? Can UNII-27Y3KJK423 influence milk supply or can UNII-27Y3KJK423 decrease milk supply in lactating mothers?

Its active metabolite is Theophylline (see it).

An expert panel considers use of UNII-27Y3KJK423 to be acceptable during breastfeeding.[1] Maternal UNII-27Y3KJK423 use may occasionally cause stimulation and irritability and fretful sleep in infants. Newborn and especially preterm infants are most likely to be affected because of their slow elimination and low serum protein binding of theophylline. There is no need to avoid UNII-27Y3KJK423 products; however, keep maternal serum theophylline concentrations in the lower part of the therapeutic range and monitor the infant for signs of theophylline side effects. Infant serum theophylline concentrations can help to determine if signs of agitation are due to theophylline. Avoiding breastfeeding for 2 hours after intravenous or 4 hours after an immediate-release oral UNII-27Y3KJK423 product can decrease the dose received by the breastfed infant.

Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal UNII-27Y3KJK423 intake of 200 mg every six hours. These effects ceased with discontinuation and recurred on rechallenge over the next 9 months. These effects were probably caused by theophylline in breastmilk. Another five infants reported in this paper showed no adverse reactions after maternal theophylline ingestion.[3] Accumulation of theophylline in infant serum appears most likely in neonates and premature infants because they eliminate theophylline slowly.[2][5]