Is CCRIS 2591 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 2591? Is CCRIS 2591 safe for nursing mother and child? Does CCRIS 2591 extracts into breast milk? Does CCRIS 2591 has any long term or short term side effects on infants? Can CCRIS 2591 influence milk supply or can CCRIS 2591 decrease milk supply in lactating mothers?

Ureidopenicillin with a similar use to ticarcillin (see specific info). It is excreted into breastmilk in a clinically insignificant amount (Baier 1982, Chaplin 1982, Wyeth 2007). Because it lacks of oral bioavailability, seems difficult any pass to the infant’s plasma through the breast milk ingested, except on premature infants and immediate neonatal period, in which there may be an increased intestinal permeability. Authorized use in infants and small infants (Chen 2009). Be aware of the likelihood of false negative cultures of febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to imbalanced intestinal flora (Ito 1993).

Limited information indicates that piperacillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Piperacillin is acceptable in nursing mothers.