Is UNII-BEA68ZVB2K Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-BEA68ZVB2K? Is UNII-BEA68ZVB2K safe for nursing mother and child? Does UNII-BEA68ZVB2K extracts into breast milk? Does UNII-BEA68ZVB2K has any long term or short term side effects on infants? Can UNII-BEA68ZVB2K influence milk supply or can UNII-BEA68ZVB2K decrease milk supply in lactating mothers?
UNII-BEA68ZVB2K lactation summary
- DrLact safety Score for UNII-BEA68ZVB2K is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-BEA68ZVB2K may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-BEA68ZVB2K may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-BEA68ZVB2K low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-BEA68ZVB2K We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-BEA68ZVB2K usage in lactation
Eslicarbazepine or S-licarbazepine is the S-enantiomer of licarbazepine (MHD), the active metabolite of oxcarbazepine (see specific information), an anti-epileptic drug considered to be of low risk during breastfeeding. Since the last update we have not found any published data on its excretion in breast milk. Given the structural equivalence and similar actions to oxcarbazepine, different effects are not likely in infants who are breastfed by mothers undergoing treatment with eslicarbazepine or oxcarbazepine, but until there is more data on this drug in relation to breastfeeding, safer known alternatives are preferred, especially in the neonatal period and in case of prematurity.
Answer by DrLact: About UNII-BEA68ZVB2K usage in lactation
No information is available on the use of eslicarbazepine during breastfeeding. However, eslicarbazepine is the active metabolite of oxcarbazepine. Limited information indicates that oxcarbazepine would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsants.
UNII-BEA68ZVB2K Side Effects in Breastfeeding
No specific information is available in mothers taking eslicarbazepine. See the LactMed record on oxcarbazepine for relevant information.
Alternate Drugs
Zonisamide(Low Risk)
Riluzole(Unsafe)
Valproic Acid(Safe)
Topiramate(Safe)
Primidone(Low Risk)
Lacosamide(Unsafe)
Phenytoin(Safe)
Phenobarbital(Low Risk)
Oxcarbazepine(Safe)
Levetiracetam(Safe)
Lamotrigine(Low Risk)
Eslicarbazepine(Low Risk)
Gabapentin(Safe)
Vigabatrin(Safe)
Felbamate(Unsafe)
Clobazam(Low Risk)
Ethosuximide(Unsafe)
Pregabalin(Low Risk)
Clonazepam(Low Risk)
Acetazolamide(Safe)
Carbamazepine(Safe)
Magnesium Sulfate(Safe)