Question

I am a breastfeeding mother and i want to know if it is safe to use Pyrilamine maleate? Is Pyrilamine maleate safe for nursing mother and child? Does Pyrilamine maleate extracts into breast milk? Does Pyrilamine maleate has any long term or short term side effects on infants? Can Pyrilamine maleate influence milk supply or can Pyrilamine maleate decrease milk supply in lactating mothers?

Pyrilamine maleate lactation summary

Pyrilamine maleate usage has low risk in breastfeeding
  • DrLact safety Score for Pyrilamine maleate is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Pyrilamine maleate may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Pyrilamine maleate may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Pyrilamine maleate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Pyrilamine maleate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Pyrilamine maleate usage in lactation

First generation antihistamine with sedative and important antimuscarinic effects. Such remarkable anticholinergic effect may inhibit lactation. At latest update no published data on excretion into breast milk were found. Drug with poor scientific support which is marketed in very few countries.Marketed as part of in many “at the counter” compounds in association poliasociación with expectorants, bronchodilators, antitussives, etc. Avoid the use of drug associations mostly while breastfeeding. Although occasional and moderate use during lactation would probably not pose a serious risk, a safer alternative should be preferred until more data on this drug related to breastfeeding is available. Topically used on the skin, it would not represent a risk during breastfeeding. Avoid applying it on the breast. Assess the child for drowsiness and inappropriate infant feeding.It is not recommended bed-sharing with your baby if you are on this medication.
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