Is Bisoprolol hemifumarate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Bisoprolol hemifumarate? Is Bisoprolol hemifumarate safe for nursing mother and child? Does Bisoprolol hemifumarate extracts into breast milk? Does Bisoprolol hemifumarate has any long term or short term side effects on infants? Can Bisoprolol hemifumarate influence milk supply or can Bisoprolol hemifumarate decrease milk supply in lactating mothers?
Bisoprolol hemifumarate lactation summary
- DrLact safety Score for Bisoprolol hemifumarate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Bisoprolol hemifumarate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Bisoprolol hemifumarate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Bisoprolol hemifumarate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Bisoprolol hemifumarate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Bisoprolol hemifumarate usage in lactation
One case with no traces of this drug in the mother's milk has been reported. Until more information is available, safer options should be preferred.
Answer by DrLact: About Bisoprolol hemifumarate usage in lactation
Because there is little published experience with bisoprolol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Bisoprolol hemifumarate Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking bisoprolol.[3] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[4][5]
Bisoprolol hemifumarate Possible Effects in Breastfeeding
A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6] Relevant published information on the effects of beta-blockade or bisoprolol during normal lactation was not found as of the revision date.
Alternate Drugs
Nebivolol(Unsafe)
Carvedilol(Low Risk)
Nadolol(Unsafe)
Timolol(Safe)
Bisoprolol(Low Risk)
Metoprolol(Safe)
Sotalol(Low Risk)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
Lidocaine(Safe)
Timolol(Safe)
Disopyramide(Safe)
Bisoprolol(Low Risk)
Mexiletine(Safe)
Metoprolol(Safe)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Propranolol(Safe)
Atenolol(Unsafe)
Propafenone(Low Risk)
Levobunolol(Low Risk)
Procainamide(Safe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Flecainide(Safe)
Amlodipine(Low Risk)
Nicardipine(Safe)
Felodipine(Low Risk)
Nifedipine(Safe)
Trandolapril(Dangerous)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Valsartan(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Terazosin(Unsafe)
Spironolactone(Safe)
Timolol(Safe)
Telmisartan(Unsafe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Prazosin(Unsafe)
Methyldopa(Safe)
Metoprolol(Safe)
Ramipril(Low Risk)
Sotalol(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Isradipine(Low Risk)
Chlorothiazide(Safe)
Indapamide(Low Risk)
Propranolol(Safe)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Bumetanide(Low Risk)
Doxazosin(Safe)
Hydrochlorothiazide(Safe)
Levobunolol(Low Risk)
Hydralazine(Safe)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Bosentan(Low Risk)
Nitrendipine(Safe)
Bendroflumethiazide(Unsafe)
Fosinopril(Low Risk)
Labetalol(Safe)
Nisoldipine(Low Risk)
Benazepril(Safe)
Verapamil(Safe)
Nebivolol(Unsafe)
Nimodipine(Safe)