Question

I am a breastfeeding mother and i want to know if it is safe to use EMD 33512? Is EMD 33512 safe for nursing mother and child? Does EMD 33512 extracts into breast milk? Does EMD 33512 has any long term or short term side effects on infants? Can EMD 33512 influence milk supply or can EMD 33512 decrease milk supply in lactating mothers?

EMD 33512 lactation summary

EMD 33512 usage has low risk in breastfeeding
  • DrLact safety Score for EMD 33512 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of EMD 33512 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that EMD 33512 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of EMD 33512 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using EMD 33512 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EMD 33512 usage in lactation

One case with no traces of this drug in the mother's milk has been reported. Until more information is available, safer options should be preferred.

Answer by DrLact: About EMD 33512 usage in lactation

Because there is little published experience with bisoprolol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

EMD 33512 Side Effects in Breastfeeding

A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking bisoprolol.[3] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[4][5]

EMD 33512 Possible Effects in Breastfeeding

A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6] Relevant published information on the effects of beta-blockade or bisoprolol during normal lactation was not found as of the revision date.

Alternate Drugs

Nebivolol(Unsafe)
Carvedilol(Low Risk)
Nadolol(Unsafe)
Timolol(Safe)
Bisoprolol(Low Risk)
Sotalol(Low Risk)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
Lidocaine(Safe)
Timolol(Safe)
Bisoprolol(Low Risk)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Atenolol(Unsafe)
Propafenone(Low Risk)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Trandolapril(Dangerous)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Valsartan(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Terazosin(Unsafe)
Timolol(Safe)
Telmisartan(Unsafe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Prazosin(Unsafe)
Ramipril(Low Risk)
Sotalol(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Isradipine(Low Risk)
Indapamide(Low Risk)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Bumetanide(Low Risk)
Doxazosin(Safe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Bosentan(Low Risk)
Fosinopril(Low Risk)
Labetalol(Safe)
Nisoldipine(Low Risk)
Verapamil(Safe)
Nebivolol(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.