Is FTY720 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use FTY720? Is FTY720 safe for nursing mother and child? Does FTY720 extracts into breast milk? Does FTY720 has any long term or short term side effects on infants? Can FTY720 influence milk supply or can FTY720 decrease milk supply in lactating mothers?

• DrLact safety Score for FTY720 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of FTY720 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that FTY720 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using FTY720 .
• It is recommended to evaluate the advantage of not breastfeeding while using FTY720 Vs not using FTY720 And continue breastfeeding.
• While using FTY720 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Immunomodulator agent indicated for the treatment of patients affected with very active type of RRMS. At latest update no published data on excretion into breast milk were found.Pharmacokinetic data (large volume of distribution and high protein binding capacity) make it unlikely its passage to breast milk in significant amounts. Its slow elimination rate with a half-life span between 6 and 9 days and its potentially serious cardiac effects suggest that a safer alternative should be preferred until more published data on this drug in relation to breastfeeding is available, especially during the neonatal period and in case prematurity.

Because there is no published experience with fingolimod during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2][3][4[