Question

I am a breastfeeding mother and i want to know if it is safe to use LY253351? Is LY253351 safe for nursing mother and child? Does LY253351 extracts into breast milk? Does LY253351 has any long term or short term side effects on infants? Can LY253351 influence milk supply or can LY253351 decrease milk supply in lactating mothers?

LY253351 lactation summary

LY253351 usage has low risk in breastfeeding
  • DrLact safety Score for LY253351 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of LY253351 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that LY253351 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of LY253351 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using LY253351 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About LY253351 usage in lactation

It is an alpha-1-adrenergic blocking agent that is used for treatment of benign prostate hypertrophy and troubles with urine voiding as obstruction or lithiasis. At latest update, relevant published data on excretion into breast milk were not found. Because of its pharmacokinetics (moderately high molecular weight and high protein-binding capacity) excretion into breast milk in significant amount is unlikely.

Alternate Drugs for Urologicals: Antispasmodics, Erectile dysfunction and Benign prostatic hypertrophy. ATC G04

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.